Molecular adsorbent recirculating system: Albumin dialysis-based extracorporeal liver assist device
نویسندگان
چکیده
منابع مشابه
Extracorporeal liver support-albumin dialysis with the Molecular Adsorbent Recirculating System (MARS).
Extracorporeal liver support has been a much studied topic throughout the last 50 years. Albumin dialysis as a therapeutic option for patients with acute liver failure or acute decompensation of chronic liver disease was introduced in the mid-nineties. The Molecular Adsorbent Recirculating System (MARS) is based on the concept of albumin dialysis and allows for the removal of protein-bound as w...
متن کاملMolecular adsorbent recirculating system and single-pass albumin dialysis in liver failure – a prospective, randomised crossover study
BACKGROUND The aim of extracorporeal albumin dialysis (ECAD) is to reduce endogenous toxins accumulating in liver failure. To date, ECAD is conducted mainly with the Molecular Adsorbents Recirculating System (MARS). However, single-pass albumin dialysis (SPAD) has been proposed as an alternative. The aim of this study was to compare the two devices with a prospective, single-centre, non-inferio...
متن کاملAlbumin dialysis with molecular adsorbent recirculating system (MARS) for the treatment of hepatic encephalopathy in liver failure.
Acute, acute-on-chronic and chronic liver diseases are major health issues worldwide, and most cases end with the need for liver transplantation. Up to 90% of the patients die waiting for an organ to be transplanted. Hepatic encephalopathy is a common neuropsychiatric syndrome that usually accompanies liver failure and impacts greatly on the quality of life. The molecular adsorbent recirculatin...
متن کاملMolecular adsorbent recirculating system (MARS).
INTRODUCTION Molecular adsorbent recirculating system (MARS) for albumin liver dialysis has been used as a bridge to liver transplantation in patients with fulminant hepatic failure (FHF). This review examines the available data on its clinical use, its technical aspects and present gaps in knowledge. METHODS Peer-reviewed journals and monographs on the subject were covered. RESULTS FHF is ...
متن کاملExtracorporeal detoxification using the molecular adsorbent recirculating system for critically ill patients with liver failure.
Liver failure resulting from different causes and its concomitant complications represent difficult-to-treat conditions with high mortality rates, despite improved therapeutic modalities in intensive care medicine. The accumulation of albumin-bound metabolites that are normally cleared by the liver, such as bilirubin and bile acids, contributes substantially to the development of multiorgan dys...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology and Hepatology
سال: 2002
ISSN: 0815-9319
DOI: 10.1046/j.1440-1746.17.s3.14.x